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doi: 10.1038/nri2190 17 BeckmannY.UzunköprüC.SubaşıoğluA
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OCT-2, and not OCT-1, mediates the genotoxic effects of the anticancer drug doxorubicin To determine whether OCT-1 regulation of OCT-2 would be involved in the differential uptake of toxic compounds, we treated worms with the chemotherapeutic drug doxorubicin at concentrations that did not lead to developmental arrest 14 , and monitored the survival of the animals by scoring brood size
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