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MDA is a byproduct of lipid peroxidation and serves as a reliable indicator of oxidative aggression, as elevated MDA levels correlate with reduced muscle strength and physical performance in post-stroke patients [74]
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44 While the alkyne-based covalent inhibitors are non-reactive against thiols, indicating proximity-driven reactivity, they formed an irreversible covalent bond with Cys25 in CatK, which was confirmed using X-ray crystal structure analysis (Fig
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