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Symptoms can vary from person to person, but may include: Nausea/vomiting Bloating or digestive issues Diarrhea Constipation Abdominal pain or gas Headache or migraine Fatigue Runny or stuffy nose Itching Rash/hives Shortness of breath Fast or irregular heart rate Flushing Low blood pressure Swelling of lips, tongue, or throat Irregular menstrual cycle In more severe cases, patients may experience cramping, high blood pressure, anxiety or dizziness, and trouble regulating body temperature

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Am J Physiol , 1978 For the physique-focused user, the implication is concrete: no IGF-1 elevation means no tissue-growth sides (no carpal tunnel, no water retention, no organ growth, no joint pain, no anabolic upside either), and no GHR-mediated insulin antagonism means no insulin-sensitivity hit — which is the specific reason this peptide slots cleanly into stacks that already carry an IGF-1 and insulin load (HGH, slin, orals)