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Non-genetic predictors of BMI loss To analyse the dependence of achieved BMI loss on non-genetic factors such as drug type, dosage and time on treatment, we fit the following model: where ‘drugType’ is an indicator variable that equals 1 for individuals using semaglutide and 0 for tirzepatide, ‘dose’ represents the dose in milligrams, days treat represents the total days on the relevant drug and ‘:’ represents an interaction term between two or more variables
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