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[DOI] [PMC free article] [PubMed] [Google Scholar] Usui T, Mise M, Hashizume T, Yabuki M, and Komuro S (2009) Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins
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Therefore, an amplification loop sustaining mitochondrial dysfunction in APAP-mediated hepatotoxicity has been suggested, involving two hits
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