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SF downregulated glycine, serine and threonine metabolism in both environments (NES -1.76 in BG, q=0.027 and −1.74 in HG, q=0.047), and One Carbon Pool by Folate was upregulated by SF, albeit only in the HG environment (1.72 in HG, q=0.026), key pathways in one carbon (1C) metabolism (Fig

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