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dihexa clinical trial humans Type_Injectable
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The different isoforms of ADH showed protection against alcoholic disorders in Han Chinese and Japanese (due to presence of ADH1B*2 ) and in African (due to presence of ADH1B*3)
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More importantly, pair-feeding and weight-matching experiments suggested the enhanced weight loss could not be explained by reduced food intake alone, leading the authors to specifically point toward five-receptor polypharmacology as a possible blueprint for future single-molecule drugs
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