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These cytokines trigger key inflammatory pathways, such as NF-kB and MAPK, which are activated by cytokines such as IL-1β and IL-18, DAMPs, TLRs, and other immune mediators (Sanz et al ., 2010, Kon et al ., 2011)
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Because the conditions used ( MOI = 0.01, 24 h) resulted in repeated IAV infectious cycles, we next performed experiments under single-replicative cycle conditions (Fig
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