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Tight junctions consist of four unique families of transmembrane proteins including occludin, claudins, junctional adhesion molecules, and tricellulin, and are considered one of the principal determinants of mucosal permeability (Fig
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During the study, 208 T2DM patients were randomly assigned to the metformin and placebo groups, where metformin was supplemented at a daily dose of 2000 mg
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