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Conversely, the mitochondria are also a target for the damaging effect of oxygen radicals (38, 65, 109)

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The first publication suggesting the potential efficacy of KMT in schizophrenia was published 60 years ago, in 1965, in an open-label pilot study of 10 females who responded well to two weeks of KMT as determined by significantly decreased symptomology by two independent clinicians, although no controls were included and dietary adherence was unclear (Table 1)