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3.2 Establishment of THRB (β/β) /RL95-2 EC cells and detection of resistance to MPA To confirm the roles of TRΞ² in the growth of EC cells and progestin resistance, THRB knockout (KO) RL95-2 cells, named as THRB (β/β) /RL95-2 cells were constructed
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In addition to oxidative stress, decreasing NADH levels with pyruvate will get Sirt1 and Sirt3 activated, leading to deactylation of mitochondrial enzymes
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