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Variable importance in projection (VIP) scores were calculated to rank metabolites based on their contribution to group separation
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197/233 DEGs co-regulated by CTCF FL and H373R mutant were associated with Hi-C interactions with CTCF and G4 peaks, and intriguingly, 107/233 DEGs were associated with persistent loops, displaying a highly significant correlation ( 7 (up to 12 for any loop and 21 for the middle loop)
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