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Absence of Systemic Endocrine Disruption# Across six Phase I/II trials running ~900 subjects, AOD-9604 produced no meaningful changes in IGF-1, fasting glucose, HbA1c, insulin sensitivity, or lipid parameters at any tested dose
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Acknowledgements This work was supported by the National Natural Science Foundation of China (82503497, 82411540241), Science and Technology Plan Project of the Health Commission of Fujian Province (2025GGA100)
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