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A 2010 study by Tudor and colleagues in Regulatory Peptides reported that BPC-157 at 10 µg/kg or 10 ng/kg i.p., given 30 minutes before falling-weight traumatic brain injury in mice, directionally reduced unconsciousness and mortality across force impulses of 0.068–0.145 Ns, with the higher dose effective at the maximum 0.159 Ns impulse — though the abstract does not report numeric mortality percentages or p-values

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Individuals with Leber’s disease, a hereditary optic nerve disorder, should avoid this medication due to the risk of exacerbating the condition