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Calcitriol has been shown to enhance autophagic activity in podocytes and tubular cells by restoring LC3-II expression and autophagic flux, while concurrently reducing apoptosis through the modulation of Bcl-2 and Bax expression (21)
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By contrast, a mixture of dKLAK-z13 (100 μg ml −1 ) and HLAH-z13 (25 μg ml −1 ) promoted massive apoptosis and cell detachment (Fig
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